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NAC

Also known as N-acetylcysteine

What it is
Precursor to glutathione and mucolytic agent
What it does
Supports glutathione synthesis and reduces mucus viscosity in respiratory tissues
Status
Widely used supplement
Evidence
Moderate. Extensive human data.
Uses
Respiratory support; antioxidant support; liver and metabolic protocols

Caution. May cause GI upset; can interact with some medications.

Summary

NAC is a derivative of the amino acid cysteine that serves as a precursor for glutathione synthesis and also acts as a mucolytic in respiratory care. It is used in antioxidant, liver, and metabolic protocols, and has a long history in clinical settings for specific indications. GI tolerance is generally good, though some people experience nausea or reflux.

Checked Jul 19, 2026.

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This entry summarises published information in plain language. It is not medical advice, a dosing recommendation or a substitute for a qualified healthcare professional. Many peptides are not approved for human use, and legal status varies by country. Check anything you rely on against primary sources.