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Creatine

Also known as Creatine monohydrate

What it is: Nitrogen-containing compound that helps regenerate ATP
What it does: Supports rapid energy production in muscle and brain during high-intensity effort
Status: Widely used supplement
Evidence: High. Extensive human data.
Uses: Strength and power; muscle mass; cognitive support under stress

Caution. Generally well tolerated; some people experience water retention or mild GI upset.

Summary

Creatine is a naturally occurring compound that helps regenerate ATP, the immediate energy currency used during short, intense efforts. It is one of the most studied sports supplements, with consistent benefits for strength, power, and lean mass, and emerging data for cognitive support under stress or sleep loss. It is typically taken daily rather than cycled.

Checked Jul 19, 2026.

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This entry summarises published information in plain language. It is not medical advice, a dosing recommendation or a substitute for a qualified healthcare professional. Many peptides are not approved for human use, and legal status varies by country. Check anything you rely on against primary sources.