Also known as Folic acid, L-5-MTHF, Methylfolate
Caution. Very high doses can mask B12 deficiency; some people prefer reduced forms.
Folate is a B-vitamin central to one-carbon metabolism, which underlies DNA synthesis, methylation reactions, and red blood cell formation. It is especially important before and during pregnancy to reduce neural tube defect risk, and is often included in B-complex formulas for cardiovascular and cognitive support. Some people choose reduced forms (5-MTHF) due to genetic variation in folate metabolism.
Checked Jul 19, 2026.
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