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GHK-Cu

Also known as Copper peptide

What it is: Copper-binding tripeptide
What it does: Studied for skin repair, collagen support, and wound-healing signaling
Status: Experimental
Evidence: Low. Mostly preclinical and topical research.
Uses: Topical skincare; tissue repair research

Caution. Human evidence is limited outside cosmetic/topical use.

Summary

GHK-Cu is a naturally occurring copper-binding peptide that modulates gene expression related to extracellular matrix remodeling, angiogenesis, and inflammation. Most evidence comes from cell and animal models plus cosmetic studies showing improved skin texture and collagen markers. Systemic use is not well characterized in humans, and most applications are topical or in wound-healing research.

Checked Jul 15, 2026.

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This entry summarises published information in plain language. It is not medical advice, a dosing recommendation or a substitute for a qualified healthcare professional. Many peptides are not approved for human use, and legal status varies by country. Check anything you rely on against primary sources.